Workflow for Screening and Quantification of the SAMHSA (NIDA) Panel in Serum Using UHPLC-TOF

Workplace drug screening was introduced in the United States in the 1980’s. President Ronald Reagan issued an order stipulating mandatory drug testing for every safety-sensitive (i.e. transportation), civil service and executive level federal employee. In 1988, drug testing legislation was passed to permit private employers to introduce policies concerning drug testing. The primary motivation for screening in the workplace is safety. Companies with employees running machinery, working with consumers, or operating vehicles often perform this procedure to comply with the aforementioned legislation. In addition, some federal and state regulations require workers in certain industries to undergo drug testing before and during employment. In the USA, drug screening is mandated and regulated by the Substance Abuse and Mental Health Services Administration (SAMHSA). Workflow for Screening and Quantification of the SAMHSA (NIDA) Panel in Serum Using UHPLC-TOF A P P L I C A T I O N N O T E